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李胜杰-助理研究员

浏览次数: 日期:2021-05-12

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基本信息

籍贯:江西省余干县      邮箱:lishengjie1104@ncu.edu.cn

出生年月:1986.11              政治面貌:中共党员

通讯地址:江西省南昌市学府大道1299号南昌大学前湖校区转化医学研究院1203

教育经历

博士:2016.09-2019.09浙江大学生物物理学专业

硕士:2011.09-2014.06南昌大学微生物学专业

本科:2006.09-2010.07江西师范大学生物科学(师范类)

工作经历:

2023.03-2024.03:新加坡国立大学,合成生物学协同创新中心(SynCTI),博士后(国家公派)

2019.09-至今:南昌大学转化医学研究院,助理研究员

2015.06-2016.08:江西省农业科学院-农业应用微生物研究所,研究实习员

2014.07-2015.05:江西省肿瘤医院生物治疗中心(与公司合办),实验员

科研方向

合成生物学技术革新及其在生物医学中的创新应用;益生菌与微生物组转化医学研究

发表论文

1Heng Wu, Jing Wei, Xiumiao Zhao, Ying Liu, Zhihang Chen, Kehong Wei, Jiachen Lu, Wenjie Chen, Meixiu Jiang, Shengjie Li*(共同通讯)and Tingtao Chen *. Neuroprotective effects of an engineered E. coli Nissle on Parkinson's disease in mice by delivering GLP-1 and modulating gut microbiota. Bioengineering & Translational Medicine, 2022, accepted.1区,Top期刊,IF=10.711

2Shengjie Li, Jing Wei* and Tingtao Chen *. Editorial: The Role of Dietary Interventions in The Regulation of Host-Microbe Interactions. Frontiers in Cellular and Infection Microbiology, 2022, 12:849508.2区,IF=5.293

3Xiaoxiao Zhao#, Shengjie Li #(共一), Jianing Ding, Jing Wei, Puyuan Tian, Hong Wei* and Tingtao Chen*. Combination of an engineered Lactococcus lactis expressing CXCL12 with light-emitting diode yellow light as a treatment for scalded skin in mice. Microbial Biotechnology, 2021, 14(5):1090-2100.2区,IF=5.813

4Shengjie Li*(兼共同通讯), Jing Wei and Tingtao Chen*. Editorial: Gut Microbiota in the Occurrence, Development and Treatment of Gut-Brain Disorders. Frontiers in Cellular and Infection Microbiology, 2021, 11:808454.2区,IF=5.293

5Shengjie Li, Yuan Gao, Qingyao Shang, Wenxuan Guo, Hui Liu, Jing Wei and Tingtao Chen*. Evidence for the existence of microbiota in the placenta and blood of pregnant mice exposed to various bacteria. Medicine in Microecology, 2021, 8:100040.(医学微生态领域重点打造新期刊)

6Shengjie Li, Jianling Cai, Hhuizhi Lu, Shuyu Mao, Shang Dai, Jing Hu, Liangyan Wang, Xiaoting Hua, Hong Xu, Bing Tian, Ye Zhao and Yuejin Hua *. N4-cytosine DNA methylation is involved in the maintenance of genomic stability in Deinococcus radiodurans. Frontiers in Microbiology, 2019, 10: 1095.2区,IF=5.640

7Huizhi Lu, Liangyan Wang, Shengjie Li, Chaoming Pan, Kaiying Cheng, Yuxia Luo, Hong Xu, Bing Tian, Ye Zhao* and Yuejin Hua*. Structure and DNA damage-dependent derepression mechanism for the XRE family member DG-DdrO. Nucleic Acids Research, 2019, 47 (18):9925-9933.1区,Top期刊,IF=16.971

8Shengjie Li, Renhui Huang, Nagendra P. Shah, Xueying Tao, Yonghua Xiong, Hua Wei. Antioxidant and antibacterial activities of exopolysaccharides from Bifidobacterium bifidum WBIN03 and Lactobacillus plantarum R315. Journal of Dairy Science. 2014, 97(12), 7334-7343.1区,Top期刊,IF=4.034

9Shengjie Li, Tingtao Chen, Feng Xu, Suqin Dong, Hengyi Xu, Yonghua Xiong, Hua Wei*. The beneficial effect of the exopolysaccharides from Bifidobacterium bifidum WBIN03 on the microbial diversity in the mice intestine. Journal of the Science of Food and Agriculture, 2014, 2 (94), 256-164.2区,Top期刊,IF=3.638

10Shengjie Li, Tingtao Chen, Suqin Dong, Yonghua Xiong, Hua Wei*, Feng Xu*. The effects of Rebaudioside A on microbial diversity in mouse intestine. Food Science and Technology Research. 2014, 94(2):256-264. 4区,IF=0.668

11Xiaomin Yu, Shengjie Li, Dong Yang, Liang Qiu, Yaoping Wu, Dengyuan Wang, Nagendra P. Shah, Feng Xu and Hua Wei*. A novel strain of Lactobacillus mucosae isolated from a Gaotian villager improves in vitro and in vivo antioxidant as well as biological properties in D-galactose-induced aging mice. Journal of dairy science, 2016, 99(2): 903-914.1区,Top期刊,IF=4.034

12Tingtao Chen, Qinglong Wu, Shengjie Li, Shunqiang Xiong, Shuying Jiang, Qianglai Tan, Zhichao Zhang, Daochen Zhu and Hua Wei. Microbiological Quality and Characteristics of Probiotic Products in China. Journal of the Science of Food and Agriculture, 2014, 94 (1): 131-138.2区,Top期刊,IF=3.638

13Tingtao Chen, Shengjie Li and Hua Wei. Antibiotic resistance capability of cultured human colonic microbiota growing in a chemostat model. Applied Biochemistry & Biotechnology, 2014, 173(3):765-774.3区,IF=2.926

14Shanshan Peng, Youjun Yang, Shengjie Li, Qinglong Wu, Shah NP, Hua Wei and Feng Xu. Immunomodulatory activities of Lactobacillus rhamnosus ZDY114 and donkey milk in BALB/c mice. International Dairy Journal, 2014, 263-266.3区,IF=3.032

15Tingtao Chen, Mengjuan Wang, Shengjie Li, Qinglong Wu, and Hua Wei. Molecular Identification of Microbial Community in Surface and Undersurface Douchi During Post-fermentation. Journal of Food Science, 2014, doi: 10.1111/1750-3841.12417.3区,IF=3.167

16Renhui Huang, Xueying Tao, Cuixiang Wan, ShengjieLi, Hengyi Xu, Feng Xu,, N. P. Shah., and Hua Wei*. In vitro probiotic characteristics of Lactobacillus plantarum ZDY 2013 and its modulatory effect on gut microbiota of mice. Journal of dairy science, 98(9), 5850-5861, 2015.

17Tingtao Chen, Qianglai Tan, Mengjuan Wang, Shunqiang Xiong, Shuying Jiang, Qinglong Wu, Shengjie Li, Hua Wei*. Identification of bacterial strains in viili by molecular taxonomy and their synergistic effects on milk curd and exopolysaccharides production. African Journal of Biotechnology. 10: 16969-16975, 2011SCI 4区).

18李胜杰,陈廷涛,董素琴,熊勇华,魏华*。双歧杆菌胞外多糖生理功能的研究概述.天然产物研究与开发, 251600-16062013

19、彭珊珊,李胜杰,陈廷涛,魏华,徐锋*。发酵驴奶乳酸菌的筛选及其生理作用初探。食品科学, 33:143-147,2013.

20、吴青龙,陈廷涛,熊顺强,姜淑英,李胜杰,魏华*。利用PCR-DGGE技术监测Lactobacillus plantarum WCFS1对小鼠肠道菌群的动态变化。南昌大学学报-理科版,35:559-563, 2012

21Tingtao ChenShengjie LiQianglai TanSuying JiangShunqiang XiongHua Wei*. Evaluation of bacterial diversity in blood and placenta of pregnant mice with oral administration of probiotics and pathogens. 2012第十三届亚太临床微生物暨感染病会议。PS1-0482012。(会议论文)

发明专利

1、华跃进,李胜杰,王梁燕,蔡建玲,DNA甲基转移酶及其可溶性异源表达和分离纯化方法。 申请号:201811291824.3,公开号:CN 109486779A

2、华跃进,李胜杰,王梁燕,蔡建玲,华孝廷,一种耐辐射奇球菌DNA甲基转移酶。申请号:201811290498.1,公开号:CN 109439636A

3、魏华,黄仁慧,许恒毅,李胜杰,徐锋,何丽华,一种风味泡菜制作方法。申请号:201510552205.5,公开号:CN 105361047A

4、魏华,黄仁慧,万翠香,李胜杰,许恒毅,陶雪莹,何丽华,含植物乳杆菌的微生态制剂,申请号:201510552654.X,公开号:CN 105112334A

科研项目

l教育部“春晖计划”合作科研项目,1万元,在研,主持

l企业合作开发项目,31万元,在研,主持

l国家自然科学基金委员会,地区科学基金项目(82260389),33万元,在研,主持

l江西省科技厅,自然科学基金面上项目20224BAB206078),10万,主持

l国家自然科学基金委员会,地区科学基金项目(82160766),34万元,在研,参与

l国家自然科学基金委员会,面上项目(31870051),59万元,结题,参与

l国家自然科学基金委员会,地区科学基金项目(31660016),40万元,结题,参与。

学术荣誉与其它:

l 省部级奖励:益生菌产业化关键技术的集成与应用,2021年中国发明协会发明创业奖创新奖一等奖,第四完成人。

l 2019年江西省高层次引进人才(四类)。

l 韩燚洋,陈建瑞,张殊玮,等。“ESAC”--Live Bacterial Drugs Targeting Malignant Tumors: High Efficacy and Low-cost Cancer Therapy。2022年第八届中国国际“互联网+”大学生创新创业大赛国家级铜奖(指导老师)。

l 陈文杰,马彦冰,何颖橙,等.“必为君”—为提高癌症患者预后而生的益生菌制剂,第十三届“挑战杯”南昌大学大学生创业计划竞赛,校级二等奖,2022年(指导老师)。

l 曾凌云,于舒月,姜汛。RecF-DrDciA蛋白互作在耐辐射奇球菌DNA损伤修复中的作用机制(2020CX283),校级创新训练项目,结题,2022

l 范锐,王佳瑶,张晶。RNA降解复合体关键核酸酶RNase Y的功能研究(项目编号:5091),科研训练项目,结题,2021

l 陈治行,王盛景,杨雯。耐辐射奇球菌类核结构与其极端抗性关系研究(项目编号:4880),科研训练项目,结题,2021

l 第十二届DNA损伤应答与人类疾病国际研讨会(The 12th international symposium on DNA Damage Response & Human Disease, isDDRHD-2021),202110月,中国,上海。

l 《耐辐射奇球菌基因组DNA甲基化研究》,中国微生物学会学术年会大会报告,201810月,中国,南昌。

l DNA metabolism, Genomics stability & Human Disease冷泉港亚洲学术会议,20186月,中国,苏州。

l RNA Modifications & Epitranscriptomics,冷泉港亚洲学术会议,201711月,中国,苏州。



所属类别: 研发团队

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